Table 2

Recovery of morphine after hot extraction and filtration

Filtration

Volume of extract

(ml)

Amount of morphine

(mg)

P versus cig.

filter alone*

None

3.0

58.9 ± 1.3

Cigarette filter

First filtrate

2.1 ± 0.1

42.4 ± 0.9

First rinse

1.0 ± 0.1

9.1 ± 1.9

Second rinse

1.1 ± 0.1

2.7 ± 0.1

Total

4.1 ± 0.1

54.3 ± 2.6

Cotton wool

First filtrate

1.6 ± 0.2

35.3 ± 4.4

First rinse

1.1 ± 0.0

12.1 ± 2.3

Second rinse

1.0 ± 0.2

5.2 ± 0.6

Total

3.8 ± 0.3

52.6 ± 3.1

0.393

0.45 μm filter

First filtrate

1.9 ± 0.2

41.2 ± 2.3

Rinse

0.9 ± 0.1

10.7 ± 2.4

Total

2.8 ± 0.2

51.8 ± 1.9

0.203

Combined filtration

Cig.+ 0.45 μm filter

4.5 ± 0.3

52.4 ± 1.6

0.400

Cig. + 0.22 μm filter

4.3 ± 0.6

49.6 ± 2.0

0.096

Data are mean ± SD, N = 3.

*Comparison of morphine recovery by Mann-Whitney U test (a non-parametric analogue of the t-test), 2-tailed. Results are consistent with parametric analysis with Games-Howell post-hoc tests.

McLean et al. Harm Reduction Journal 2009 6:37   doi:10.1186/1477-7517-6-37